Last edited by Voodoojin
Friday, May 8, 2020 | History

3 edition of Pharmaceutical Aspects of Oligonucleotides (Taylor & Francis Series in Pharmaceutical Sciences) found in the catalog.

Pharmaceutical Aspects of Oligonucleotides (Taylor & Francis Series in Pharmaceutical Sciences)

  • 68 Want to read
  • 5 Currently reading

Published by CRC .
Written in English

    Subjects:
  • Molecular biology,
  • Drugs - Adverse Effects,
  • Pharmaceutical Chemistry,
  • Medical,
  • Medical / Nursing,
  • Pharmacology,
  • Pharmacy,
  • Medical / Pharmacology,
  • Oligonucleotides,
  • Therapeutic use,
  • adverse effects

  • Edition Notes

    ContributionsPatrick Couvreur (Editor), Claude Malvy (Editor)
    The Physical Object
    FormatHardcover
    Number of Pages321
    ID Numbers
    Open LibraryOL9537216M
    ISBN 10074840841X
    ISBN 109780748408412

    About this book Introduction The reader will be introduced to various aspects of the fundamentals of nanotechnology based drug delivery systems and the application of these systems for the delivery of small molecules, proteins, peptides, oligonucleotides and genes.   The second edition of Pharmaceutical Stress Testing: Predicting Drug Degradation provides a practical and scientific guide to designing, executing and interpreting stress testing studies for drug substance and drug product. This is the only guide available to tackle this subject in-depth.

      Providing a broad introduction to the growing field, this book explores the way in which peptides, proteins, nucleic acids and carbohydrates used therapeutically. With help of numerous illustrations, it covers both the compounds and how therapeutics exert their influence throuhg an understanding of biological processes. * Includes the latest developments in the field * Covers the Author: Christine Bladon. Pharmaceutical Experimental Design and Interpretation (2nd Edition), Armstrong & James , 0 8 (Hbk) Pharmaceutical Production Facilities (2nd Edition), Cole , 0 4 (Hbk) Pharmaceutical Aspects of Oligonucleotides, Couvreur & Malvy (Eds) , 0 X (Hbk) Pharmaceutical Formulation.

      POTENTIAL ADVANTAGES: There are several aspects of antisense therapy utilizing oligonucleotides that are potentially advantageous over traditional drug mechanisms. Such as: 1) Oligonucleotides may be manufactured quickly, some times within one week, or two and only the sequence of a gene is all that is needed.   The Aptamer Handbook: Functional Oligonucleotides and Their Applications - Ebook written by Sven Klussmann. Read this book using Google Play Books app on your PC, android, iOS devices. Download for offline reading, highlight, bookmark or take notes while you read The Aptamer Handbook: Functional Oligonucleotides and Their : Sven Klussmann.


Share this book
You might also like
Bishops transcripts of parish registers, 1800-1903, transferred to the Middlesex County Record Office on 7th January, 1965

Bishops transcripts of parish registers, 1800-1903, transferred to the Middlesex County Record Office on 7th January, 1965

recognition of Herman Melville

recognition of Herman Melville

Head direction cells and the neural mechansims of spatial orientation

Head direction cells and the neural mechansims of spatial orientation

Ride the Devil Wind

Ride the Devil Wind

Pharmacology

Pharmacology

Supplement to Catalogue of theses

Supplement to Catalogue of theses

Wind and wave

Wind and wave

Medieval village, manor and monastery.

Medieval village, manor and monastery.

Practical work at the Cavendish laboratory: Heat.

Practical work at the Cavendish laboratory: Heat.

Olivers adventure in the haunted house.

Olivers adventure in the haunted house.

Copyright and patents, or, Property in thought

Copyright and patents, or, Property in thought

hand press

hand press

Pharmaceutical Aspects of Oligonucleotides (Taylor & Francis Series in Pharmaceutical Sciences) Download PDF EPUB FB2

Pharmaceutical Aspects of Oligonucleotides (Taylor & Francis Series in Pharmaceutical Sciences): Medicine & Health Science Books @ mat: Hardcover. Therefore, although PNA is a very good structural mimic of DNA in terms of its ability to form stable and sequence-selective complexes with complementary DNA or RNA oligonucleotides, it has unique chemical and physicochemical properties (Hyrup and Nielsen, ; Good and Nielsen, ).Cited by: 1st Edition Published on September 2, by CRC Press Oligonucleotides diffuse poorly through biological barriers, including cell membranes.

Pharmaceutical Aspects of Oligonucleotides book are also rap Pharmaceutical Aspects of Oligonucleotides - 1st Edition - Patrick Co. Pharmaceutical Aspects of Oligonucleotides - CRC Press Book Oligonucleotides diffuse poorly through biological barriers, including cell membranes.

They. Oligonucleotides diffuse poorly through biological barriers, including cell membranes. They are also rapidly degraded in vivo by nucleuses.

Aiming to improve the administration of compounds, the book. Oligonucleotide-based drugs, in particular antisense oligonucleotides, are part of a growing number of pharmaceutical and biotech programs progressing to treat a wide range of indications including cancer, cardiovascular, neurodegenerative, neuromuscular, and respiratory diseases, as well as other severe and rare : Hardcover.

pharmaceutical aspects of oligonucleotides taylor and francis series in pharmaceutical sciences Posted By Hermann Hesse Media TEXT ID eee9e Online PDF Ebook Epub Library pharmaceutical science and technology fourth edition is a must have reference guide for all laboratories and libraries in the pharmaceutical field bringing together leaders.

Oligonucleotide-based drugs, in particular antisense oligonucleotides, are part of a growing number of pharmaceutical and biotech programs progressing to treat a wide range of indications including cancer, cardiovascular, neurodegenerative, neuromuscular, and respiratory diseases, as well as other severe and rare diseases.

Synthesis of Therapeutic Oligonucleotides covers a broad range of topics in the field that are of high relevance to researchers, including the synthesis of natural and chemically modified oligonucleotides, the development of novel nucleic acid analogs, industrial scale synthesis and purification of oligonucleotides, and important aspects of.

This article, which is the first in a planned series intended to address chemistry, manufacturing, and control (CMC) aspects of therapeutic oligonucleotides, examines the topic of specifications for active pharmaceutical ingredients (APIs).

The authors attempt to present basic scientific considerations for the broadest range of oligonucleotide by: Pharmaceutical aspects of oligonucleotides. [Patrick Couvreur; Claude Malvy;] -- Oligonucleotides with base sequences complementary (antisense) to a specific RNA or DNA offer the exciting potential of selectively modulating the expression of an individual gene.

While primarily for people entering the pharmaceutical industry, those established in the field will benefit from the multiple examples and matrices as well as integration of related systems.

Equipment Qualification in the Pharmaceutical Industry provides students and pharmaceutical scientists a guideline for the preparation and execution of qualification (installation, operational, and performance) protocols.

Quality Aspects of Oligonucleotide Drug Development: Specifications for Active Pharmaceutical Ingredients. This article, which is the first in a planned series intended to address chemistry, manufacturing, and control (CMC) aspects of therapeutic oligonucleotides, examines the topic of specifications for active pharmaceutical ingredients (APIs).

CMC Regulatory Considerations for Oligonucleotide Drug Products: FDA Perspective Mohan Sapru, M.S., Ph.D.

CMC Lead for Cardiovascular and Renal Products Office of New Drug Products Member, Emerging Technology Team (ETT) Office of Pharmaceutical Quality, CDER, FDA e Size: KB. Crucial aspects of LC-MS bioanalytical method development (e.g., pre-analytical considerations, derivation strategies, stability, non-specific binding) in addition to sample preparation techniques for challenging molecules (e.g., lipids, peptides, proteins, oligonucleotides, antibody-drug conjugates).

Pharmaceutical Stress Testing book. Predicting Drug Degradation, Second Edition. Pharmaceutical Stress Testing. Practical aspects of conducting photostability stress testing. With David Clapham, Allen C.

Templeton, Lee J. Klein, Mark H. Kleinman. View by: 5. The editors have provided a well-balanced framework for introductory as well as more detailed education in various aspects of pharmaceutical biotechnology and the production, biopharmaceutics, and clinical pharmacology of biotechnology-produced drugs.

and oligonucleotides and siRNA has enhanced these important concepts in the text. Provided the status of therapeutic oligonucleotides, including their different types and FDA approvals. • Highlighted the typical chemical modifications of ASOs and siRNAs, their delivery systems and common impurities.

• Reviewed the characterization of oligonucleotides by ion-pair RPLC, AEX, MMC, HILIC, SEC and 2D-LC. •Author: Alexandre Goyon, Peter Yehl, Kelly Zhang.

This is an essential reference book for Pharmaceutical Scientists and those working in Quality Assurance and Drug Development (analytical sciences, formulations, chemical process, project management).

Read Pharmaceutical Aspects of Oligonucleotides (Taylor & Francis Series in Pharmaceutical. Thehyper. PDF Download Social and Behavioral Aspects of Pharmaceutical Care PDF Full Ebook. Imen Download Social And Behavioral Aspects Of Pharmaceutical Care Free Books.

Suyel. [PDF Download] Social And Behavioral Aspects Of. Oligonucleotides are growing in importance in the pharmaceutical and biotechnology industries as therapeutic medicines.

However, their structure and analysis are challenging and require a different approach to existing medicinal products. This book reviews the most up-to-date analytical strategies for synthetic oligonucleotides.The second edition of Pharmaceutical Stress Testing: Predicting Drug Degradation provides a practical and scientific guide to designing, executing and interpreting stress testing studies for drug substance and drug product.

This is the only guide available to tackle this subject in-depth.Reviewing fundamentals and offering guidelines for drug discovery and development, this book is a practical guide covering all key aspects of this increasingly popular area of pharmacology and biotech and pharma research, from the basic science behind antisense oligonucleotides chemistry, toxicology, manufacturing, to safety assessments, the.